"CHA-Station" (Complex Ejector)
CHA-Station is developed to separate Adipose Derived Stem Cells (ADSCs) or PPP in a safe and easy way so that local surgeons also can separate ADSCs to do Cell Assisted Lipotransfer (CAL) even in their local clinics, preventing air contamination possibility.
With this system, no bothering secondary surgery is necessary.
1. Short seperation time 30~40 mins
2. Autologous cells are separable (PRP, PPP, ADSCs, Purified fat)
3. Closed system for no air contamination possibility
4. State of the air design
5. Small size for easy movement
6. Syringe use, no pipette work
7. ADSC and Platelets counting within 30 seconds
8. Previous consumables can be used in this system
9. Providing Human grade collagenase, not animal test collagenase
¨1. Embryonic Stem Cell
¨2. Adult Stem Cell
¨1) Bone Marrow - Bone Marrow Stem Cell
¨2) Adipose Tissue – Adipose Derived Stem Cell(ADSC) - CHA-STATION
¨SVF (Stromal Vascular Fraction)
¨1. Final 5ml result including ADSCs
¨2. ADSCs, Endothelial Cells, Red Blood Cells, other Regenerative Cells are included in SVF. (Tissue Engineering. 7:212-213, 2001).
¨3. Because of time, cost, and difficulty of ADSC separation, SVF is being used instead of ADSC by most of the clinics and research institutes all over the world.
¨4. IFATS, International Federation of Adipose Therapeutics and Science, which is the most prestigious association regarding ADSC, agreed in 2009 that SVF can be called also as ADSC. There is no restriction for calling SVF counting as ADSC counting. (IFATS 2009 Oral Abstracts. 17)
¨CAL Treatment (Cell Assisted Lipotransfer)
1.The method to inject the mixture of lipoaspirate and extracted stem cells.
2.Based on Dr. Yoshimura` paper in which more than 40 patients were tested for breast augmentation with CAL treatment, up to 70% of fat survival rate was confirmed (Aesth Plast Surg 2008;32:48-55).
Stem Cell = Blue Ocean?
1.Stem Cell`s diverse diversification is considered as cell therapy`s future.
2.Thus, the need for harvesting large amount of healthy stem cells is increasing.
What is ADSCs?
(Adipose Derived Stem Cells)
1.In 2001, Dr. Zuk successfully separated stem cells from adipose tissue. (Tissue Engineering. 7:212-228, 2001)
2.Thus, adipose tissue became known as the best donor site for harvesting stem cells in large amount and in the easiest way, compared to stem cells in marrow, peripheral blood vessels, or umbilical cord.
ADSCs Combination with Lipotransfer
(CAL, Cell-Assisted Lipotransfer)
1.After harvesting technique of ADSCs is known by the research of Dr. Zuk (Tissue Engineering. 7:212-228, 2001), a number of research of ADSCs was conducted for years.
2.In 2008, Dr. Yoshimura in Japan conducted a research with about 40 patients for more than 2 years and found out that if ADSCs are mixed with previous lipotranfer surgery conducted in plastic surgery, dermatology, or urology cell viability increased up to 70% because of angiogenesis role of ADSCs (Aesth Plast Surg 2008;32:48-55).
Limitations of previous ADSCs separation products
1.After that, there have been several ADSCs separation products based on the separation protocol of Dr. Zuk research and sold to local clinics of plastic surgery, dermatology, and urology for doing CAL treatment of Dr. Yoshimura.
2.However, there has been many technical problems, for example, air contamination possibility or long separation time and research has been conducted for overcoming those problems by several stem cell research institute. One of them is CHA BIOMED in CHA Hospital group.